Found 11 hits for monomerid = 50010101 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Muscarinic acetylcholine receptor M1
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
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| 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Group Research Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 38: 805-15 (1990)
BindingDB Entry DOI: 10.7270/Q2H993P0 |
More data for this Ligand-Target Pair | |
CHRM4
(RABBIT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | UniProtKB/TrEMBL
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| 1.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Group Research Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 38: 805-15 (1990)
BindingDB Entry DOI: 10.7270/Q2H993P0 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
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| 1.78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Group Research Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 38: 805-15 (1990)
BindingDB Entry DOI: 10.7270/Q2H993P0 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
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| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description Displacement of [3H]pirenzepine from muscarinic acetylcholine receptor M1 in rat cortex homogenates |
J Med Chem 34: 2984-9 (1991)
BindingDB Entry DOI: 10.7270/Q27H1K5M |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health
Curated by PDSP Ki Database
| |
Mol Pharmacol 35: 469-76 (1989)
BindingDB Entry DOI: 10.7270/Q2V69H2Z |
More data for this Ligand-Target Pair | |
CHRM4
(Chick) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | KEGG
UniProtKB/SwissProt
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| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Group Research Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 38: 805-15 (1990)
BindingDB Entry DOI: 10.7270/Q2H993P0 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 32.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Group Research Ltd.
Curated by PDSP Ki Database
| |
Mol Pharmacol 38: 805-15 (1990)
BindingDB Entry DOI: 10.7270/Q2H993P0 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(RAT) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description Displacement of [3H](-)-quinuclidinyl benzilate(QNB) from muscarinic (M2) receptor in rat heart homogenates |
J Med Chem 34: 2984-9 (1991)
BindingDB Entry DOI: 10.7270/Q27H1K5M |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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| 244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Mental Health
Curated by PDSP Ki Database
| |
Mol Pharmacol 35: 469-76 (1989)
BindingDB Entry DOI: 10.7270/Q2V69H2Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type I I alpha subunit
(Homo sapiens (Human)) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
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| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea... |
J Med Chem 28: 381-8 (1985)
BindingDB Entry DOI: 10.7270/Q2Z321T8 |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM50010101
(2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarbo...)Show InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |