BindingDB PrimarySearch

BDBM50012994 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL538542::NPA,(+)::SKF-76783::cid_11957529

SMILES: CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key: InChIKey=BTGAJCKRXPNBFI-OAHLLOKOSA-N

Data: 7 KI 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50012994
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	645	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
Broad Institute Curated by PubChem BioAssay					More data for this Ligand-Target Pair
POsterior Segregation family member (pos-1) (Caenorhabditis elegans)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.56E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
Broad Institute Curated by PubChem BioAssay					More data for this Ligand-Target Pair