BDBM50013320 CHEMBL3263034

SMILES: CC(C)Oc1ccc(cc1NC(=O)c1cnccn1)N1CCN(Cc2ccc(C)cc2)CC1

InChI Key: InChIKey=YJYSRJUZHKSHGJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50013320 (CHEMBL3263034) Show SMILES CC(C)Oc1ccc(cc1NC(=O)c1cnccn1)N1CCN(Cc2ccc(C)cc2)CC1 Show InChI InChI=1S/C26H31N5O2/c1-19(2)33-25-9-8-22(16-23(25)29-26(32)24-17-27-10-11-28-24)31-14-12-30(13-15-31)18-21-6-4-20(3)5-7-21/h4-11,16-17,19H,12-15,18H2,1-3H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Antagonist activity at CCR5 (unknown origin) expressed in human MOLT4 cells assessed as inhibition of RANTES-stimulated calcium mobilization treated ...				Bioorg Med Chem Lett 24: 2319-23 (2014) Article DOI: 10.1016/j.bmcl.2014.03.073 BindingDB Entry DOI: 10.7270/Q29C6ZZM
					More data for this Ligand-Target Pair