Found 13 hits for monomerid = 50015142 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Arachidonate 12-lipoxygenase
(Rattus norvegicus) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Invitro inhibition of rat platelet 12-lipoxygenase |
J Med Chem 32: 1836-42 (1989)
BindingDB Entry DOI: 10.7270/Q2VT1R21 |
More data for this Ligand-Target Pair | |
Arachidonate 5-lipoxygenase
(Rattus norvegicus) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against RBL-1 5-LO |
J Med Chem 30: 574-80 (1987)
BindingDB Entry DOI: 10.7270/Q2QN67BB |
More data for this Ligand-Target Pair | |
Arachidonate 5-lipoxygenase
(Rattus norvegicus) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1) |
J Med Chem 33: 992-8 (1990)
BindingDB Entry DOI: 10.7270/Q2WW7GNM |
More data for this Ligand-Target Pair | |
Arachidonate 5-lipoxygenase
(Rattus norvegicus) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1) |
J Med Chem 33: 992-8 (1990)
BindingDB Entry DOI: 10.7270/Q2WW7GNM |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC1 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC2 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC6 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC8 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC4 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC5 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC7 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC9 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50015142
(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)Show InChI InChI=1S/C10H13NO2/c12-10(11-13)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,13H,4,7-8H2,(H,11,12) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of Harvard and MIT
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC3 |
ACS Med Chem Lett 2: 39-42 (2011)
Article DOI: 10.1021/ml1001954 BindingDB Entry DOI: 10.7270/Q2TH8NQJ |
More data for this Ligand-Target Pair | |