BDBM50016802 CHEMBL3273848

SMILES: CCN1CC(CN(C)c2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=Nc2c(N)nc(N)nc12

InChI Key: InChIKey=KZFYYAOPKMGEHQ-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50016802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Lactobacillus casei)	BDBM50016802 (CHEMBL3273848) Show SMILES CCN1CC(CN(C)c2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=Nc2c(N)nc(N)nc12 |r,c:26| Show InChI InChI=1S/C22H28N8O5/c1-3-30-11-13(25-17-18(23)27-22(24)28-19(17)30)10-29(2)14-6-4-12(5-7-14)20(33)26-15(21(34)35)8-9-16(31)32/h4-7,15H,3,8-11H2,1-2H3,(H,26,33)(H,31,32)(H,34,35)(H4,23,24,27,28)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MTX-resistant Lactobacillus casei dihydrofolate reductase				J Med Chem 20: 1323-7 (1977) BindingDB Entry DOI: 10.7270/Q2SX6FRK
					More data for this Ligand-Target Pair
Thymidylate Synthase (TS) (Lactobacillus casei)	BDBM50016802 (CHEMBL3273848) Show SMILES CCN1CC(CN(C)c2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=Nc2c(N)nc(N)nc12 |r,c:26| Show InChI InChI=1S/C22H28N8O5/c1-3-30-11-13(25-17-18(23)27-22(24)28-19(17)30)10-29(2)14-6-4-12(5-7-14)20(33)26-15(21(34)35)8-9-16(31)32/h4-7,15H,3,8-11H2,1-2H3,(H,26,33)(H,31,32)(H,34,35)(H4,23,24,27,28)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetase				J Med Chem 20: 1323-7 (1977) BindingDB Entry DOI: 10.7270/Q2SX6FRK
					More data for this Ligand-Target Pair