BDBM50018211 3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-butyric acid::CHEMBL36094

SMILES: CC(CC(O)=O)NC(=O)C(CC(=O)NO)Cc1ccccc1

InChI Key: InChIKey=UKHIXBAHBRUVMS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50018211 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-but...) Show SMILES CC(CC(O)=O)NC(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C15H20N2O5/c1-10(7-14(19)20)16-15(21)12(9-13(18)17-22)8-11-5-3-2-4-6-11/h2-6,10,12,22H,7-9H2,1H3,(H,16,21)(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50018211 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-but...) Show SMILES CC(CC(O)=O)NC(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C15H20N2O5/c1-10(7-14(19)20)16-15(21)12(9-13(18)17-22)8-11-5-3-2-4-6-11/h2-6,10,12,22H,7-9H2,1H3,(H,16,21)(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	445	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50018211 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-but...) Show SMILES CC(CC(O)=O)NC(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C15H20N2O5/c1-10(7-14(19)20)16-15(21)12(9-13(18)17-22)8-11-5-3-2-4-6-11/h2-6,10,12,22H,7-9H2,1H3,(H,16,21)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase activity in rabbit kidney with 20 nM [3H]D-Ala2-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50018211 (3-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-but...) Show SMILES CC(CC(O)=O)NC(=O)C(CC(=O)NO)Cc1ccccc1 Show InChI InChI=1S/C15H20N2O5/c1-10(7-14(19)20)16-15(21)12(9-13(18)17-22)8-11-5-3-2-4-6-11/h2-6,10,12,22H,7-9H2,1H3,(H,16,21)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase activity in rabbit kidney with 20 nM [3H]-D-Ala2-Leu-enkephalin as substrate				J Med Chem 32: 1497-503 (1989) BindingDB Entry DOI: 10.7270/Q2610Z9F
					More data for this Ligand-Target Pair