BDBM50018225 2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propionic acid 2-diethylamino-ethyl ester::CHEMBL416974

SMILES: CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(OC(=O)N(C)C)cc1

InChI Key: InChIKey=JNWQHLUYBJFULU-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50018225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50018225 (2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...) Show SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(OC(=O)N(C)C)cc1 Show InChI InChI=1S/C24H32N2O4/c1-6-26(7-2)17-18-29-22(27)24(3,19-11-9-8-10-12-19)20-13-15-21(16-14-20)30-23(28)25(4)5/h8-16H,6-7,17-18H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Binding affinity was determined from the inhibition of contraction of guinea pig ileum which has Muscarinic acetylcholine receptor M2 subtype.				J Med Chem 32: 1522-8 (1989) BindingDB Entry DOI: 10.7270/Q2VQ3374
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Bos taurus)	BDBM50018225 (2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...) Show SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(OC(=O)N(C)C)cc1 Show InChI InChI=1S/C24H32N2O4/c1-6-26(7-2)17-18-29-22(27)24(3,19-11-9-8-10-12-19)20-13-15-21(16-14-20)30-23(28)25(4)5/h8-16H,6-7,17-18H2,1-5H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypes				J Med Chem 32: 1522-8 (1989) BindingDB Entry DOI: 10.7270/Q2VQ3374
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM50018225 (2-(4-Dimethylcarbamoyloxy-phenyl)-2-phenyl-propion...) Show SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(OC(=O)N(C)C)cc1 Show InChI InChI=1S/C24H32N2O4/c1-6-26(7-2)17-18-29-22(27)24(3,19-11-9-8-10-12-19)20-13-15-21(16-14-20)30-23(28)25(4)5/h8-16H,6-7,17-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of anticholinesterase activity by their ability to inactivate human serum butyrylcholinesterase				J Med Chem 32: 1522-8 (1989) BindingDB Entry DOI: 10.7270/Q2VQ3374
					More data for this Ligand-Target Pair