BDBM50023335 CHEMBL3334540
SMILES: FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
InChI Key: InChIKey=FLAOLXIVHDPGJX-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50023335 (CHEMBL3334540) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited Curated by ChEMBL | Assay Description Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA | J Med Chem 57: 7577-89 (2014) Article DOI: 10.1021/jm500510f BindingDB Entry DOI: 10.7270/Q2JD4ZCR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50023335 (CHEMBL3334540) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited Curated by ChEMBL | Assay Description Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay | J Med Chem 57: 7577-89 (2014) Article DOI: 10.1021/jm500510f BindingDB Entry DOI: 10.7270/Q2JD4ZCR | |||||||||||
More data for this Ligand-Target Pair |