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BDBM50023883 4-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-but-2-en-1-ol::CHEMBL50388

SMILES: Nc1nccc2n(C\C=C\CO)cnc12

InChI Key: InChIKey=UPOPWDPXTWJIEQ-OWOJBTEDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023883   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))
BDBM50023883
PNG
(4-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-but-2-en-1-...)
Show SMILES Nc1nccc2n(C\C=C\CO)cnc12
Show InChI InChI=1S/C10H12N4O/c11-10-9-8(3-4-12-10)14(7-13-9)5-1-2-6-15/h1-4,7,15H,5-6H2,(H2,11,12)/b2-1+
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.23E+3n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Evaluated for the 50% inhibition of bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase


J Med Chem 31: 1729-38 (1988)


BindingDB Entry DOI: 10.7270/Q2HM5920
More data for this
Ligand-Target Pair