BDBM50029662 3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-6-methyl-1H-pyridin-2-one::CHEMBL336237

SMILES: CCc1c(C)[nH]c(=O)c(N)c1Sc1cc(C)cc(C)c1

InChI Key: InChIKey=SBXYUVDYGNRQAF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029662 (3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-6-...) Show SMILES CCc1c(C)[nH]c(=O)c(N)c1Sc1cc(C)cc(C)c1 Show InChI InChI=1S/C16H20N2OS/c1-5-13-11(4)18-16(19)14(17)15(13)20-12-7-9(2)6-10(3)8-12/h6-8H,5,17H2,1-4H3,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair