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SMILES: CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)cc12)C(F)(F)F)C(=O)C1CC1

InChI Key: InChIKey=SVCPVHQMPURRRU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034992   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM50034992
PNG
(CHEMBL3343115)
Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)cc12)C(F)(F)F)C(=O)C1CC1
Show InChI InChI=1S/C25H25F3N2O3/c1-3-29(24(33)16-5-6-16)13-18-11-19(25(26,27)28)7-9-21(18)30-14-17(12-23(31)32)20-8-4-15(2)10-22(20)30/h4,7-11,14,16H,3,5-6,12-13H2,1-2H3,(H,31,32)
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n/an/a 119n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...

Bioorg Med Chem Lett 24: 5123-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.029
BindingDB Entry DOI: 10.7270/Q2CF9RRW
More data for this
Ligand-Target Pair