BDBM50036835 1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol::1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol(Di chloroisoproterenol)::CHEMBL30816::Dichloroisoproterenol,(+/-)

SMILES: CC(C)NCC(O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VKMGSWIFEHZQRS-UHFFFAOYSA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50036835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Pisa Curated by ChEMBL					Assay Description Binding affinity against beta1-adrenergic receptor in rat brain				J Med Chem 37: 1518-25 (1994) BindingDB Entry DOI: 10.7270/Q2V69HM4
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database									Mol Pharmacol 12: 568-80 (1976) BindingDB Entry DOI: 10.7270/Q2ZK5F5P
					More data for this Ligand-Target Pair
ADRB2 (BOVINE)	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Pisa Curated by ChEMBL					Assay Description Binding afinity against beta2-adrenergic receptor in bovine lung				J Med Chem 37: 1518-25 (1994) BindingDB Entry DOI: 10.7270/Q2V69HM4
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	977	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Pisa Curated by ChEMBL					Assay Description Inhibitory concentration against beta-2-adrenergic receptor in isolated guinea pig tracheal strips				J Med Chem 37: 1518-25 (1994) BindingDB Entry DOI: 10.7270/Q2V69HM4
					More data for this Ligand-Target Pair
Sodium channel protein type I I alpha subunit (Homo sapiens (Human))	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...				J Med Chem 28: 381-8 (1985) BindingDB Entry DOI: 10.7270/Q2Z321T8
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (GUINEA PIG)	BDBM50036835 (1-(3,4-Dichloro-phenyl)-2-isopropylamino-ethanol |...) Show SMILES CC(C)NCC(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C11H15Cl2NO/c1-7(2)14-6-11(15)8-3-4-9(12)10(13)5-8/h3-5,7,11,14-15H,6H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Pisa Curated by ChEMBL					Assay Description Inhibitory concentration against beta-1-adrenergic receptor in isolated guinea pig atria				J Med Chem 37: 1518-25 (1994) BindingDB Entry DOI: 10.7270/Q2V69HM4
					More data for this Ligand-Target Pair