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SMILES: CCN1C(=O)CC2(CCN(C)CC2)C1=O

InChI Key: InChIKey=UIHKDOBBVHGTAQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50038212 (2-Ethyl-8-methyl-2,8-diaza-spiro[4.5]decane-1,3-di...) Show SMILES CCN1C(=O)CC2(CCN(C)CC2)C1=O Show InChI InChI=1S/C11H18N2O2/c1-3-13-9(14)8-11(10(13)15)4-6-12(2)7-5-11/h3-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description In vitro binding affinity for muscarinic M1 receptor by displacing [3H]-Pirenzepine binding on rat brain homogenate.				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50038212 (2-Ethyl-8-methyl-2,8-diaza-spiro[4.5]decane-1,3-di...) Show SMILES CCN1C(=O)CC2(CCN(C)CC2)C1=O Show InChI InChI=1S/C11H18N2O2/c1-3-13-9(14)8-11(10(13)15)4-6-12(2)7-5-11/h3-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Drug Discovery Research Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine from rat cortex membrane expressing muscarinic M1 receptor				J Med Chem 36: 2292-9 (1993) BindingDB Entry DOI: 10.7270/Q2W66MDV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50038212 (2-Ethyl-8-methyl-2,8-diaza-spiro[4.5]decane-1,3-di...) Show SMILES CCN1C(=O)CC2(CCN(C)CC2)C1=O Show InChI InChI=1S/C11H18N2O2/c1-3-13-9(14)8-11(10(13)15)4-6-12(2)7-5-11/h3-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Drug Discovery Research Curated by ChEMBL					Assay Description Compound tested in vitro for displacement of [3H]quinuclidinyl benzilate from rat cerebellum membrane expressing muscarinic M2 receptor				J Med Chem 36: 2292-9 (1993) BindingDB Entry DOI: 10.7270/Q2W66MDV
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50038212 (2-Ethyl-8-methyl-2,8-diaza-spiro[4.5]decane-1,3-di...) Show SMILES CCN1C(=O)CC2(CCN(C)CC2)C1=O Show InChI InChI=1S/C11H18N2O2/c1-3-13-9(14)8-11(10(13)15)4-6-12(2)7-5-11/h3-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description M2 agonist activity estimated by depression of isolated guinea pig left atrium				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
					More data for this Ligand-Target Pair