BDBM50040928 4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-isoindolylamino]benzonitrile::CHEMBL267869

SMILES: O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12

InChI Key: InChIKey=KQTHJPWPAZKUSZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclic AMP-dependent protein kinase (PKA) (Oryctolagus cuniculus (Rabbit))	BDBM50040928 (4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...) Show SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12 Show InChI InChI=1S/C22H13N5O2/c23-11-13-1-5-15(6-2-13)25-19-9-17-18(22(29)27-21(17)28)10-20(19)26-16-7-3-14(12-24)4-8-16/h1-10,25-26H,(H,27,28,29)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity was determined against protein kinase A (PKA) of rabbit				J Med Chem 37: 1015-27 (1994) BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040928 (4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...) Show SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12 Show InChI InChI=1S/C22H13N5O2/c23-11-13-1-5-15(6-2-13)25-19-9-17-18(22(29)27-21(17)28)10-20(19)26-16-7-3-14(12-24)4-8-16/h1-10,25-26H,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Limited Curated by ChEMBL					Assay Description Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)				J Med Chem 37: 1015-27 (1994) BindingDB Entry DOI: 10.7270/Q2M32TTP
					More data for this Ligand-Target Pair