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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50040928'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50040928
PNG
(4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...)
Show SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12
Show InChI InChI=1S/C22H13N5O2/c23-11-13-1-5-15(6-2-13)25-19-9-17-18(22(29)27-21(17)28)10-20(19)26-16-7-3-14(12-24)4-8-16/h1-10,25-26H,(H,27,28,29)
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KEGG

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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Ciba-Geigy Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)

J Med Chem 37: 1015-27 (1994)


BindingDB Entry DOI: 10.7270/Q2M32TTP
More data for this
Ligand-Target Pair