BDBM50042997 4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1,2-diol(2,6-DiFNE)::CHEMBL435802

SMILES: NCC(O)c1c(F)cc(O)c(O)c1F

InChI Key: InChIKey=OGFDKGAXVKUJBQ-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50042997 (4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...) Show SMILES NCC(O)c1c(F)cc(O)c(O)c1F Show InChI InChI=1S/C8H9F2NO3/c9-3-1-4(12)8(14)7(10)6(3)5(13)2-11/h1,5,12-14H,2,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from adrenergic alpha 2 receptor of rat cerebral cortical membranes				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Rattus norvegicus (Rat))	BDBM50042997 (4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...) Show SMILES NCC(O)c1c(F)cc(O)c(O)c1F Show InChI InChI=1S/C8H9F2NO3/c9-3-1-4(12)8(14)7(10)6(3)5(13)2-11/h1,5,12-14H,2,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]dihydroalprenolol from adrenergic beta 1 receptor of rat cerebral cortical membranes				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair
Adrenergic receptor beta (Rattus norvegicus (Rat))	BDBM50042997 (4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...) Show SMILES NCC(O)c1c(F)cc(O)c(O)c1F Show InChI InChI=1S/C8H9F2NO3/c9-3-1-4(12)8(14)7(10)6(3)5(13)2-11/h1,5,12-14H,2,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptor				J Med Chem 36: 3947-55 (1994) BindingDB Entry DOI: 10.7270/Q2QC044C
					More data for this Ligand-Target Pair