BDBM50043359 1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H-anthracen-9-one::CHEMBL133058

SMILES: Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1

InChI Key: InChIKey=QKVUGRSIFXNRPS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043359 (1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H...) Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1 Show InChI InChI=1S/C22H16O5/c23-13-9-7-12(8-10-13)11-18(26)19-14-3-1-5-16(24)20(14)22(27)21-15(19)4-2-6-17(21)25/h1-10,19,23-25H,11H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Bos taurus)	BDBM50043359 (1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H...) Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1 Show InChI InChI=1S/C22H16O5/c23-13-9-7-12(8-10-13)11-18(26)19-14-3-1-5-16(24)20(14)22(27)21-15(19)4-2-6-17(21)25/h1-10,19,23-25H,11H2	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität Regensburg Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).				J Med Chem 36: 4099-107 (1994) BindingDB Entry DOI: 10.7270/Q2G44PC2
					More data for this Ligand-Target Pair