BDBM50045493 CHEMBL3310116

SMILES: Cl.[#6]-c1cccc2-c3ccc(cc3-[#6](-[#8])-c12)-[#6](=O)\[#7]=[#6](/[#7])-[#7]

InChI Key: InChIKey=SKLCKJYAZFZKJB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50045493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50045493 (CHEMBL3310116) Show SMILES Cl.[#6]-c1cccc2-c3ccc(cc3-[#6](-[#8])-c12)-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C16H15N3O2/c1-8-3-2-4-11-10-6-5-9(15(21)19-16(17)18)7-12(10)14(20)13(8)11/h2-7,14,20H,1H3,(H4,17,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation counting				Bioorg Med Chem 22: 4323-37 (2014) Article DOI: 10.1016/j.bmc.2014.05.027 BindingDB Entry DOI: 10.7270/Q2X63PK3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50045493 (CHEMBL3310116) Show SMILES Cl.[#6]-c1cccc2-c3ccc(cc3-[#6](-[#8])-c12)-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C16H15N3O2/c1-8-3-2-4-11-10-6-5-9(15(21)19-16(17)18)7-12(10)14(20)13(8)11/h2-7,14,20H,1H3,(H4,17,18,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation counting				Bioorg Med Chem 22: 4323-37 (2014) Article DOI: 10.1016/j.bmc.2014.05.027 BindingDB Entry DOI: 10.7270/Q2X63PK3
					More data for this Ligand-Target Pair