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SMILES: Cc1cccc(OCCCn2cnc(c2Cl)-c2ccccc2)c1NC(=O)NCC(C)(C)C

InChI Key: InChIKey=LMVJPINFMJHLDK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047546 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES Cc1cccc(OCCCn2cnc(c2Cl)-c2ccccc2)c1NC(=O)NCC(C)(C)C Show InChI InChI=1S/C25H31ClN4O2/c1-18-10-8-13-20(21(18)29-24(31)27-16-25(2,3)4)32-15-9-14-30-17-28-22(23(30)26)19-11-6-5-7-12-19/h5-8,10-13,17H,9,14-16H2,1-4H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047546 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES Cc1cccc(OCCCn2cnc(c2Cl)-c2ccccc2)c1NC(=O)NCC(C)(C)C Show InChI InChI=1S/C25H31ClN4O2/c1-18-10-8-13-20(21(18)29-24(31)27-16-25(2,3)4)32-15-9-14-30-17-28-22(23(30)26)19-11-6-5-7-12-19/h5-8,10-13,17H,9,14-16H2,1-4H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair