BDBM50051213 CHEMBL278025::Thiophen-2-ylmethyl-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester

SMILES: O=C(NCc1cccs1)OCCCc1cnc[nH]1

InChI Key: InChIKey=VDIHTJOZRXHYEC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50051213 (CHEMBL278025 | Thiophen-2-ylmethyl-carbamic acid 3...) Show SMILES O=C(NCc1cccs1)OCCCc1cnc[nH]1 Show InChI InChI=1S/C12H15N3O2S/c16-12(14-8-11-4-2-6-18-11)17-5-1-3-10-7-13-9-15-10/h2,4,6-7,9H,1,3,5,8H2,(H,13,15)(H,14,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity of the compound against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.				J Med Chem 39: 1157-63 (1996) Article DOI: 10.1021/jm9507688 BindingDB Entry DOI: 10.7270/Q2SF2V7G
					More data for this Ligand-Target Pair