BDBM50052691 CHEMBL114199::N-[5-(4-Cyclohexyl-butyryl)-2-methyl-phenyl]-nicotinamide

SMILES: Cc1ccc(cc1NC(=O)c1cccnc1)C(=O)CCCC1CCCCC1

InChI Key: InChIKey=UJNRBVZSCOAMLG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL receptor (Homo sapiens (Human))	BDBM50052691 (CHEMBL114199 | N-[5-(4-Cyclohexyl-butyryl)-2-methy...) Show SMILES Cc1ccc(cc1NC(=O)c1cccnc1)C(=O)CCCC1CCCCC1 Show InChI InChI=1S/C23H28N2O2/c1-17-12-13-19(22(26)11-5-9-18-7-3-2-4-8-18)15-21(17)25-23(27)20-10-6-14-24-16-20/h6,10,12-16,18H,2-5,7-9,11H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Concentration at which one-half the maximum Low density lipoprotein receptor upregulation is observed in HepG2 cells				J Med Chem 39: 3343-56 (1996) Article DOI: 10.1021/jm960153q BindingDB Entry DOI: 10.7270/Q2FT8K4S
					More data for this Ligand-Target Pair