BDBM50056898 2-Hydroxy-benzoic acid N'-(2-hydroxy-benzyl)-hydrazide::2-hydroxy-N'-[(2- hydroxyphenyl)methyl]benzohydrazide (Compound 4)::CHEMBL433983

SMILES: Oc1ccccc1CNNC(=O)c1ccccc1O

InChI Key: InChIKey=SJSJXRMQLWUZCN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Integrase (Human immunodeficiency virus type 1)	BDBM50056898 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzyl)-hydra...) Show SMILES Oc1ccccc1CNNC(=O)c1ccccc1O Show InChI InChI=1S/C14H14N2O3/c17-12-7-3-1-5-10(12)9-15-16-14(19)11-6-2-4-8-13(11)18/h1-8,15,17-18H,9H2,(H,16,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy, Nirma University, Ahmedabad, 382 481, India.					Assay Description HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.				Chem Biol Drug Des 83: 154-66 (2014) Article DOI: 10.1111/cbdd.12207 BindingDB Entry DOI: 10.7270/Q2QR4VSW
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50056898 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzyl)-hydra...) Show SMILES Oc1ccccc1CNNC(=O)c1ccccc1O Show InChI InChI=1S/C14H14N2O3/c17-12-7-3-1-5-10(12)9-15-16-14(19)11-6-2-4-8-13(11)18/h1-8,15,17-18H,9H2,(H,16,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase enzyme by 3'-processing method				J Med Chem 40: 937-41 (1997) Article DOI: 10.1021/jm960755+ BindingDB Entry DOI: 10.7270/Q2154G4R
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50056898 (2-Hydroxy-benzoic acid N'-(2-hydroxy-benzyl)-hydra...) Show SMILES Oc1ccccc1CNNC(=O)c1ccccc1O Show InChI InChI=1S/C14H14N2O3/c17-12-7-3-1-5-10(12)9-15-16-14(19)11-6-2-4-8-13(11)18/h1-8,15,17-18H,9H2,(H,16,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase enzyme				J Med Chem 40: 937-41 (1997) Article DOI: 10.1021/jm960755+ BindingDB Entry DOI: 10.7270/Q2154G4R
					More data for this Ligand-Target Pair