BDBM50060458 (Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid::CHEMBL435382
SMILES: OC(=O)CCC\C=C/C[C@H]1[C@@H]2CC[C@@H](C2)[C@@H]1NS(=O)(=O)c1ccc2ccccc2c1
InChI Key: InChIKey=FIPYJDOEJWQULW-VGQIUGRMSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50060458 ((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human platelets | J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50060458 ((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assay | J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50060458 ((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranes | J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50060458 ((Z)-7-[(1R,2S,3S,4S)-3-(Naphthalene-2-sulfonylamin...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assay | J Med Chem 40: 3504-7 (1997) Article DOI: 10.1021/jm970343g BindingDB Entry DOI: 10.7270/Q2959GP9 | |||||||||||
More data for this Ligand-Target Pair |