Found 5 hits for monomerid = 50066979 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lactate dehydrogenase B (LDHB)
(Homo sapiens (Human)) | BDBM50066979
(2,3-Dihydroxy-6,7-dimethyl-4-propyl-naphthalene-1-...)Show InChI InChI=1S/C16H18O4/c1-4-5-10-11-6-8(2)9(3)7-12(11)13(16(19)20)15(18)14(10)17/h6-7,17-18H,4-5H2,1-3H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico School of Medicine
Curated by ChEMBL
| Assay Description inhibitory activity against Human Lactate Dehydrogenase (LDH-M) |
J Med Chem 41: 3879-87 (1998)
Article DOI: 10.1021/jm980334n BindingDB Entry DOI: 10.7270/Q298864G |
More data for this Ligand-Target Pair | |
Lactate dehydrogenase A (LDHA)
(Homo sapiens (Human)) | BDBM50066979
(2,3-Dihydroxy-6,7-dimethyl-4-propyl-naphthalene-1-...)Show InChI InChI=1S/C16H18O4/c1-4-5-10-11-6-8(2)9(3)7-12(11)13(16(19)20)15(18)14(10)17/h6-7,17-18H,4-5H2,1-3H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico School of Medicine
Curated by ChEMBL
| Assay Description inhibitory activity against P. falciparum lactate dehydrogenase (pLDH) |
J Med Chem 41: 3879-87 (1998)
Article DOI: 10.1021/jm980334n BindingDB Entry DOI: 10.7270/Q298864G |
More data for this Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50066979
(2,3-Dihydroxy-6,7-dimethyl-4-propyl-naphthalene-1-...)Show InChI InChI=1S/C16H18O4/c1-4-5-10-11-6-8(2)9(3)7-12(11)13(16(19)20)15(18)14(10)17/h6-7,17-18H,4-5H2,1-3H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-CRO
Curated by ChEMBL
| Assay Description Competitive inhibition of human LDH5 in presence of NADH |
J Med Chem 59: 487-96 (2016)
BindingDB Entry DOI: 10.7270/Q2B27X41 |
More data for this Ligand-Target Pair | |
Lactate dehydrogenase B (LDHB)
(Homo sapiens (Human)) | BDBM50066979
(2,3-Dihydroxy-6,7-dimethyl-4-propyl-naphthalene-1-...)Show InChI InChI=1S/C16H18O4/c1-4-5-10-11-6-8(2)9(3)7-12(11)13(16(19)20)15(18)14(10)17/h6-7,17-18H,4-5H2,1-3H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute-CRO
Curated by ChEMBL
| Assay Description Competitive inhibition of human LDH1 in presence of NADH |
J Med Chem 59: 487-96 (2016)
BindingDB Entry DOI: 10.7270/Q2B27X41 |
More data for this Ligand-Target Pair | |
Lactate dehydrogenase B (LDHB)
(Homo sapiens (Human)) | BDBM50066979
(2,3-Dihydroxy-6,7-dimethyl-4-propyl-naphthalene-1-...)Show InChI InChI=1S/C16H18O4/c1-4-5-10-11-6-8(2)9(3)7-12(11)13(16(19)20)15(18)14(10)17/h6-7,17-18H,4-5H2,1-3H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico School of Medicine
Curated by ChEMBL
| Assay Description inhibitory activity against Human Lactate Dehydrogenase (LDH-H) |
J Med Chem 41: 3879-87 (1998)
Article DOI: 10.1021/jm980334n BindingDB Entry DOI: 10.7270/Q298864G |
More data for this Ligand-Target Pair | |