null

SMILES: C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O

InChI Key: InChIKey=AIOPERPCMDNFTR-ZYOSVBKOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50066996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50066996 ((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O Show InChI InChI=1S/C17H19NO4/c1-2-6-13-15-14(22-16(13)19)9-10-18(15)17(20)21-11-12-7-4-3-5-8-12/h2-5,7-8,13-15H,1,6,9-11H2/t13-,14-,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50066996 ((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O Show InChI InChI=1S/C17H19NO4/c1-2-6-13-15-14(22-16(13)19)9-10-18(15)17(20)21-11-12-7-4-3-5-8-12/h2-5,7-8,13-15H,1,6,9-11H2/t13-,14-,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50066996 ((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O Show InChI InChI=1S/C17H19NO4/c1-2-6-13-15-14(22-16(13)19)9-10-18(15)17(20)21-11-12-7-4-3-5-8-12/h2-5,7-8,13-15H,1,6,9-11H2/t13-,14-,15?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of cathepsin G with a preincubation time of 15 min				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50066996 ((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O Show InChI InChI=1S/C17H19NO4/c1-2-6-13-15-14(22-16(13)19)9-10-18(15)17(20)21-11-12-7-4-3-5-8-12/h2-5,7-8,13-15H,1,6,9-11H2/t13-,14-,15?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhition of thrombin with a preincubation time of 15 min				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50066996 ((3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES C=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O Show InChI InChI=1S/C17H19NO4/c1-2-6-13-15-14(22-16(13)19)9-10-18(15)17(20)21-11-12-7-4-3-5-8-12/h2-5,7-8,13-15H,1,6,9-11H2/t13-,14-,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 min				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair