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TargetChymotrypsinogen A
LigandBDBM50066996
Substrate/Competitorn/a
Meas. Tech.ChEMBL_49929 (CHEMBL660312)
IC50 4860.0±n/a nM
Citation Macdonald, SJBelton, DJBuckley, DMSpooner, JEAnson, MSHarrison, LAMills, KUpton, RJDowle, MDSmith, RAMolloy, CRRisley, C Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition. J Med Chem41:3919-22 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Chymotrypsinogen A
Name:Chymotrypsinogen A
Synonyms:Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:Serine protease
Mol. Mass.:25670.88
Organism:Bos taurus (bovine)
Description:n/a
Residue:245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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  Blast E-value cutoff:
BDBM50066996
n/a
NameBDBM50066996
Synonyms:(3S,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester | CHEMBL125796
TypeSmall organic molecule
Emp. Form.C17H19NO4
Mol. Mass.301.3371
SMILESC=CC[C@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O
Structure
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