null

SMILES: CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12

InChI Key: InChIKey=HVBZENRYJFPJCR-ZDGBYWQASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50066998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin G (Homo sapiens (Human))	BDBM50066998 ((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12 Show InChI InChI=1S/C12H17NO4/c1-3-5-8-10-9(17-11(8)14)6-7-13(10)12(15)16-4-2/h3,8-10H,1,4-7H2,2H3/t8-,9+,10?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of cathepsin G with a preincubation time of 15 min				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50066998 ((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12 Show InChI InChI=1S/C12H17NO4/c1-3-5-8-10-9(17-11(8)14)6-7-13(10)12(15)16-4-2/h3,8-10H,1,4-7H2,2H3/t8-,9+,10?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhition of thrombin with a preincubation time of 15 min.				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50066998 ((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12 Show InChI InChI=1S/C12H17NO4/c1-3-5-8-10-9(17-11(8)14)6-7-13(10)12(15)16-4-2/h3,8-10H,1,4-7H2,2H3/t8-,9+,10?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of Chymotrypsinogen with a preincubation time of 15 min				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50066998 ((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...) Show SMILES CCOC(=O)N1CC[C@@H]2OC(=O)[C@H](CC=C)C12 Show InChI InChI=1S/C12H17NO4/c1-3-5-8-10-9(17-11(8)14)6-7-13(10)12(15)16-4-2/h3,8-10H,1,4-7H2,2H3/t8-,9+,10?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 15 min.				J Med Chem 41: 3919-22 (1998) Article DOI: 10.1021/jm981026s BindingDB Entry DOI: 10.7270/Q2X34WMC
					More data for this Ligand-Target Pair