BDBM50074558 Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)propyl(trimethyl)ammonium}pentane; dibromide::CHEMBL168840

SMILES: C[N+](C)(CCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=OSALRKZRWVYPFR-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50074558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (GUINEA PIG)	BDBM50074558 (Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...) Show SMILES C[N+](C)(CCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C33H46N4O4/c1-36(2,24-14-20-34-30(38)26-16-8-9-17-27(26)31(34)39)22-12-6-5-7-13-23-37(3,4)25-15-21-35-32(40)28-18-10-11-19-29(28)33(35)41/h8-11,16-19H,5-7,12-15,20-25H2,1-4H3/q+2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	389	n/a	n/a	n/a	n/a
University of Wuerzburg Curated by ChEMBL					Assay Description Ability to dissociate radioligand [3H]NMS from muscarinic acetylcholine receptor M2 of porcine heart				J Med Chem 46: 1390-407 (2003) Article DOI: 10.1021/jm021077w BindingDB Entry DOI: 10.7270/Q2JD50JS
					More data for this Ligand-Target Pair
Cholinergic, muscarinic (GUINEA PIG)	BDBM50074558 (Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...) Show SMILES C[N+](C)(CCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C33H46N4O4/c1-36(2,24-14-20-34-30(38)26-16-8-9-17-27(26)31(34)39)22-12-6-5-7-13-23-37(3,4)25-15-21-35-32(40)28-18-10-11-19-29(28)33(35)41/h8-11,16-19H,5-7,12-15,20-25H2,1-4H3/q+2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2				J Med Chem 42: 849-58 (1999) Article DOI: 10.1021/jm981023f BindingDB Entry DOI: 10.7270/Q22806RB
					More data for this Ligand-Target Pair