BDBM50079063 6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-pyridine-2-carboxylic acid::BDBM50222604::CHEMBL89634

SMILES: NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O

InChI Key: InChIKey=IVKDUEUEOMQWRK-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50079063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant carbonic anhydrase II				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A.P.S. University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II (CAII)				Bioorg Med Chem Lett 13: 447-53 (2003) BindingDB Entry DOI: 10.7270/Q2668GC9
					More data for this Ligand-Target Pair
Carbonic anhydrase (Bos taurus (bovine))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A.P.S. University Curated by ChEMBL					Assay Description Inhibition of bovine carbonic anhydrase IV (CAIV)				Bioorg Med Chem Lett 13: 447-53 (2003) BindingDB Entry DOI: 10.7270/Q2668GC9
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A.P.S. University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase I (CAI)				Bioorg Med Chem Lett 13: 447-53 (2003) BindingDB Entry DOI: 10.7270/Q2668GC9
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50079063 (6-(2,3-Dichloro-4,6-disulfamoyl-phenylcarbamoyl)-p...) Show SMILES NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)c(Cl)c1Cl)S(N)(=O)=O Show InChI InChI=1S/C13H10Cl2N4O7S2/c14-9-7(27(16,23)24)4-8(28(17,25)26)11(10(9)15)19-12(20)5-2-1-3-6(18-5)13(21)22/h1-4H,(H,19,20)(H,21,22)(H2,16,23,24)(H2,17,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).				J Med Chem 42: 2641-50 (1999) Article DOI: 10.1021/jm9900523 BindingDB Entry DOI: 10.7270/Q2J67HMK
					More data for this Ligand-Target Pair