BDBM50079558 CHEMBL3417482

SMILES: CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1

InChI Key: InChIKey=DUBMUGYFNOQVHS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079558 (CHEMBL3417482) Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 115: 191-200 (2016) BindingDB Entry DOI: 10.7270/Q28K7BZ9
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079558 (CHEMBL3417482) Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1 Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair