BDBM50082020 2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-phenoxy]-phenyl}-acetamide::CHEMBL139982

SMILES: Oc1c(-c2cccc(Oc3ccccc3NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key: InChIKey=NBROMBBAOJLKSU-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50082020 (2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-17-6-1-2-7-19(17)31-15-5-3-4-13(10-15)21-22(29)16-9-8-14(25)11-18(16)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50082020 (2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...) Show SMILES Oc1c(-c2cccc(Oc3ccccc3NC(=O)CCl)c2)c(=O)[nH]c2cc(Cl)ccc12 Show InChI InChI=1S/C23H16Cl2N2O4/c24-12-20(28)26-17-6-1-2-7-19(17)31-15-5-3-4-13(10-15)21-22(29)16-9-8-14(25)11-18(16)27-23(21)30/h1-11H,12H2,(H,26,28)(H2,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Université Louis Pasteur Curated by ChEMBL					Assay Description Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...				J Med Chem 42: 4394-404 (1999) BindingDB Entry DOI: 10.7270/Q2HT2NJB
					More data for this Ligand-Target Pair