BDBM50082229 (2R,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-2,N*1*-dihydroxy-3-naphthalen-2-ylmethyl-succinamide::CHEMBL108737

SMILES: CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)[C@H](O)C(=O)NO)C(C)(C)C

InChI Key: InChIKey=XWXXVHYNTNIDBW-FGTMMUONSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50082229 ((2R,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)[C@H](O)C(=O)NO)C(C)(C)C Show InChI InChI=1S/C22H29N3O5/c1-22(2,3)18(21(29)23-4)24-19(27)16(17(26)20(28)25-30)12-13-9-10-14-7-5-6-8-15(14)11-13/h5-11,16-18,26,30H,12H2,1-4H3,(H,23,29)(H,24,27)(H,25,28)/t16-,17+,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase(MMP-1)				Bioorg Med Chem Lett 9: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2MK6C37
					More data for this Ligand-Target Pair
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50082229 ((2R,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...) Show SMILES CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)[C@H](O)C(=O)NO)C(C)(C)C Show InChI InChI=1S/C22H29N3O5/c1-22(2,3)18(21(29)23-4)24-19(27)16(17(26)20(28)25-30)12-13-9-10-14-7-5-6-8-15(14)11-13/h5-11,16-18,26,30H,12H2,1-4H3,(H,23,29)(H,24,27)(H,25,28)/t16-,17+,18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against IgE receptor				Bioorg Med Chem Lett 9: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2MK6C37
					More data for this Ligand-Target Pair