BDBM50082336 CHEMBL322378::N-(4-Benzoyl-2-methyl-phenyl)-2-(R)-octahydro-quinolizin-1-yl-acetamide

SMILES: Cc1cc(ccc1NC(=O)CC1CCCN2CCCC[C@H]12)C(=O)c1ccccc1

InChI Key: InChIKey=UYQFMKJXWOUBBI-GWQXNCQPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50082336 (CHEMBL322378 | N-(4-Benzoyl-2-methyl-phenyl)-2-(R)...) Show SMILES Cc1cc(ccc1NC(=O)CC1CCCN2CCCC[C@H]12)C(=O)c1ccccc1 Show InChI InChI=1S/C25H30N2O2/c1-18-16-21(25(29)19-8-3-2-4-9-19)12-13-22(18)26-24(28)17-20-10-7-15-27-14-6-5-11-23(20)27/h2-4,8-9,12-13,16,20,23H,5-7,10-11,14-15,17H2,1H3,(H,26,28)/t20?,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Scienze Farmaceutiche - Università di Genova Curated by ChEMBL					Assay Description Displacement of [3H]-methylscopolamine binding to muscarinic M3 receptor in submaxillary salivary glands of rats.				Bioorg Med Chem Lett 9: 3031-4 (1999) BindingDB Entry DOI: 10.7270/Q2V40TD2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50082336 (CHEMBL322378 | N-(4-Benzoyl-2-methyl-phenyl)-2-(R)...) Show SMILES Cc1cc(ccc1NC(=O)CC1CCCN2CCCC[C@H]12)C(=O)c1ccccc1 Show InChI InChI=1S/C25H30N2O2/c1-18-16-21(25(29)19-8-3-2-4-9-19)12-13-22(18)26-24(28)17-20-10-7-15-27-14-6-5-11-23(20)27/h2-4,8-9,12-13,16,20,23H,5-7,10-11,14-15,17H2,1H3,(H,26,28)/t20?,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Scienze Farmaceutiche - Università di Genova Curated by ChEMBL					Assay Description Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.				Bioorg Med Chem Lett 9: 3031-4 (1999) BindingDB Entry DOI: 10.7270/Q2V40TD2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50082336 (CHEMBL322378 | N-(4-Benzoyl-2-methyl-phenyl)-2-(R)...) Show SMILES Cc1cc(ccc1NC(=O)CC1CCCN2CCCC[C@H]12)C(=O)c1ccccc1 Show InChI InChI=1S/C25H30N2O2/c1-18-16-21(25(29)19-8-3-2-4-9-19)12-13-22(18)26-24(28)17-20-10-7-15-27-14-6-5-11-23(20)27/h2-4,8-9,12-13,16,20,23H,5-7,10-11,14-15,17H2,1H3,(H,26,28)/t20?,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Scienze Farmaceutiche - Università di Genova Curated by ChEMBL					Assay Description Displacement of [3H]-methylscopolamine binding to muscarinic M2 receptor in rat heart.				Bioorg Med Chem Lett 9: 3031-4 (1999) BindingDB Entry DOI: 10.7270/Q2V40TD2
					More data for this Ligand-Target Pair