BDBM50083674 CHEMBL3422944

SMILES: CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1

InChI Key: InChIKey=SBTIGFAQSZYTIC-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50083674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50083674 (CHEMBL3422944) Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate after 30 mins by fluorescence assay				Eur J Med Chem 97: 289-305 (2015) Article DOI: 10.1016/j.ejmech.2015.04.064 BindingDB Entry DOI: 10.7270/Q29S1SR3
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50083674 (CHEMBL3422944) Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 mins				Eur J Med Chem 97: 289-305 (2015) Article DOI: 10.1016/j.ejmech.2015.04.064 BindingDB Entry DOI: 10.7270/Q29S1SR3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50083674 (CHEMBL3422944) Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 60 mins followed by substrate addition b...				Eur J Med Chem 97: 289-305 (2015) Article DOI: 10.1016/j.ejmech.2015.04.064 BindingDB Entry DOI: 10.7270/Q29S1SR3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50083674 (CHEMBL3422944) Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 30 mins followed by substrate addition b...				Eur J Med Chem 97: 289-305 (2015) Article DOI: 10.1016/j.ejmech.2015.04.064 BindingDB Entry DOI: 10.7270/Q29S1SR3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50083674 (CHEMBL3422944) Show SMILES CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H26ClN3O4/c1-2-32-24(30)22-16-23(29(28-22)20-13-11-18(26)12-14-20)17-7-6-10-21(15-17)33-25(31)27-19-8-4-3-5-9-19/h6-7,10-16,19H,2-5,8-9H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate preincubated with protein for 0 min followed by substrate addition by ...				Eur J Med Chem 97: 289-305 (2015) Article DOI: 10.1016/j.ejmech.2015.04.064 BindingDB Entry DOI: 10.7270/Q29S1SR3
					More data for this Ligand-Target Pair