BDBM50084054 6'-Chloro-1-methyl-1,2,5,6-tetrahydro-[3,3']bipyridinyl; compound with (Z)-but-2-enedioic acid::CHEMBL1181055::CHEMBL154087

SMILES: CN1CCC=C(C1)c1ccc(Cl)nc1

InChI Key: InChIKey=YWDRNTZRCJXPPD-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50084054 (6'-Chloro-1-methyl-1,2,5,6-tetrahydro-[3,3']bipyri...) Show SMILES CN1CCC=C(C1)c1ccc(Cl)nc1 |c:4| Show InChI InChI=1S/C11H13ClN2/c1-14-6-2-3-10(8-14)9-4-5-11(12)13-7-9/h3-5,7H,2,6,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Targacept, Inc. Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR				J Med Chem 55: 9181-94 (2012) Article DOI: 10.1021/jm3006542 BindingDB Entry DOI: 10.7270/Q2W0972W
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50084054 (6'-Chloro-1-methyl-1,2,5,6-tetrahydro-[3,3']bipyri...) Show SMILES CN1CCC=C(C1)c1ccc(Cl)nc1 |c:4| Show InChI InChI=1S/C11H13ClN2/c1-14-6-2-3-10(8-14)9-4-5-11(12)13-7-9/h3-5,7H,2,6,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentration				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
					More data for this Ligand-Target Pair