BindingDB PrimarySearch

BDBM50084959 11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo-[2,3-f]indole-3,4'-piperidine](SB-224289)::4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl-1'-methylspiro[3,5,6,7-tetrahydro-2H-furo[2,3-f]indole-3,4'-(hexahydropyridine)]-5-ylmethanone::CHEMBL281350::SB-224289::[2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-yl]-[3-(1-methyl-piperidine)-2,3,6,7-tetrahydro-1-oxa-5-aza-s-indacen-5-yl]-methanone

SMILES: CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1

InChI Key: InChIKey=ATQMRMGXINTJHV-UHFFFAOYSA-N

Data: 39 KI 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50084959
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1B receptor subtype				Bioorg Med Chem Lett 7: 3183-3188 (1997) Article DOI: 10.1016/S0960-894X(97)10164-0 BindingDB Entry DOI: 10.7270/Q23R0SW9
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Columbia University College of Physicians and Surgeons Curated by ChEMBL					Assay Description In vitro binding affinity towards cloned human 5-HT1B receptor using [3H]5-carboximidotryptamine as radioligand				Bioorg Med Chem Lett 15: 4786-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.024 BindingDB Entry DOI: 10.7270/Q2NP23ZZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1D receptor subtype				Bioorg Med Chem Lett 7: 3183-3188 (1997) Article DOI: 10.1016/S0960-894X(97)10164-0 BindingDB Entry DOI: 10.7270/Q23R0SW9
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human 5-hydroxytryptamine 2C receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
Serotonin 4 (5-HT4) receptor (Sus scrofa)	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against piglet hippocampus 5-hydroxytryptamine 4 receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Muscarinic acetylcholine receptor M2				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Dopamine receptor D2				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Muscarinic acetylcholine receptor M1				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Alpha-2A adrenergic receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Alpha-1A adrenergic receptor (rat submaxillary gland)				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Beta-1 adrenergic receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Alpha-1B adrenergic receptor (rat liver ,[3H] prazosin)				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Histamine H1 receptor.				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards Histamine H2 receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
ADRA2B (MOUSE)	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Alpha-2B adrenergic receptor (NG 108-15 cells) using [3H]RX-821002) as radioligand				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Dopamine receptor D3				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Affinity for 5-hydroxytryptamine 1A receptor subtype				Bioorg Med Chem Lett 7: 3183-3188 (1997) Article DOI: 10.1016/S0960-894X(97)10164-0 BindingDB Entry DOI: 10.7270/Q23R0SW9
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human cloned Beta-2 adrenergic receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
Vernalis Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 2A receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
Vernalis Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human 5-hydroxytryptamine 1A receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
Vernalis Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human 5-hydroxytryptamine 1E receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human 5-hydroxytryptamine 1F receptor				J Med Chem 41: 1218-35 (1998) Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 125: 202-8 (1998) Article DOI: 10.1038/sj.bjp.0702059 BindingDB Entry DOI: 10.7270/Q2PC30XV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition affinity against 5-HT-1D receptor in bovine caudate nucleus using radio binding assay				J Med Chem 43: 517-25 (2000) BindingDB Entry DOI: 10.7270/Q2WM1CNB
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of 5-hydroxytryptamine reuptake				J Med Chem 43: 517-25 (2000) BindingDB Entry DOI: 10.7270/Q2WM1CNB
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assay				J Med Chem 43: 517-25 (2000) BindingDB Entry DOI: 10.7270/Q2WM1CNB
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50084959 (11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition activity against 5-hydroxytryptamine 1A receptor in rat hippocampus membranes using radio binding assays				J Med Chem 43: 517-25 (2000) BindingDB Entry DOI: 10.7270/Q2WM1CNB
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair