Found 43 hits for monomerid = 50085536 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA2 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA1 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase VA
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
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| 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA5A by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase
(Dicentrarchus labrax) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | UniProtKB/TrEMBL
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| 4.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gumushane University
Curated by ChEMBL
| Assay Description Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assay |
Bioorg Med Chem Lett 21: 4259-62 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.071 BindingDB Entry DOI: 10.7270/Q2PC32Q0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 6.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA7 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6 (CA-VI)
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt
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| Article PubMed
| 6.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA6 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 6.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA9 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase XIV
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
Reactome pathway KEGG
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| Article PubMed
| 7.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA14 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase III
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA3 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA12 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA4 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase XIII
(Mus musculus (mouse)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 9.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse CA13 by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Carbonic Anhydrase VB
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 9.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA5B by stopped-flow CO2 hydration assay |
Bioorg Med Chem 18: 2159-64 (2010)
Article DOI: 10.1016/j.bmc.2010.01.076 BindingDB Entry DOI: 10.7270/Q2GQ6ZP1 |
More data for this Ligand-Target Pair | |
Procollagen-proline,2-oxoglutarate-4-dioxygenase
(Gallus gallus (Chicken)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
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| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
| Assay Description Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase. |
J Biol Chem 261: 7819-23 (1986)
BindingDB Entry DOI: 10.7270/Q2SJ1J6Z |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| 7.58E+5 | -4.25 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ataturk University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s... |
Chem Biol Drug Des 75: 515-20 (2010)
Article DOI: 10.1111/j.1747-0285.2010.00965.x BindingDB Entry DOI: 10.7270/Q23F4N46 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 1.05E+6 | -4.06 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ataturk University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s... |
Chem Biol Drug Des 75: 515-20 (2010)
Article DOI: 10.1111/j.1747-0285.2010.00965.x BindingDB Entry DOI: 10.7270/Q23F4N46 |
More data for this Ligand-Target Pair | |
Selectin E
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| Article PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Revotar Biopharmaceuticals AG
Curated by ChEMBL
| Assay Description Inhibition of human E-selectin after 2 hrs |
J Med Chem 50: 1101-15 (2007)
Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6 |
More data for this Ligand-Target Pair | |
Nitric Oxide Synthase, inducible
(Mus musculus (mouse)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng Kung University
Curated by ChEMBL
| Assay Description Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cells |
Bioorg Med Chem 16: 9867-70 (2008)
Article DOI: 10.1016/j.bmc.2008.09.021 BindingDB Entry DOI: 10.7270/Q2125TK2 |
More data for this Ligand-Target Pair | |
Squalene monooxygenase
(Rattus norvegicus) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | Reactome pathway KEGG
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| n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Shizuoka
Curated by ChEMBL
| Assay Description Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia... |
J Nat Prod 64: 1010-4 (2001)
BindingDB Entry DOI: 10.7270/Q25Q4X03 |
More data for this Ligand-Target Pair | |
Human immunodeficiency virus type 1 reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
UniProtKB/TrEMBL
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| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toledo
Curated by ChEMBL
| Assay Description Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTP |
Bioorg Med Chem Lett 11: 2763-7 (2001)
BindingDB Entry DOI: 10.7270/Q2X92BTR |
More data for this Ligand-Target Pair | |
Autoinducer 2-binding periplasmic protein luxP
(Vibrio harveyi) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
KEGG
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| Article PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia State University
Curated by ChEMBL
| Assay Description Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrs |
Bioorg Med Chem Lett 18: 1567-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.081 BindingDB Entry DOI: 10.7270/Q2DB81KV |
More data for this Ligand-Target Pair | |
Plasminogen activator inhibitor-1
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | 7.8 | 23 |
University of Michigan
| Assay Description Enzyme activity assay using human and murine PAI-1. |
J Biol Chem 285: 7892-902 (2010)
Article DOI: 10.1074/jbc.M109.067967 BindingDB Entry DOI: 10.7270/Q2ZC81FC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Matrix metalloproteinase-7 (MMP7)
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
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Patents
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| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.3 | 22 |
Schering Plough Research Institute
| Assay Description Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Alpha-(2,3)-(N)-sialyltransferase
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | 7.3 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Alpha-(1,3)-fucosyltransferase IV
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | 7.3 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Alpha-(1,3)-fucosyltransferase VII
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | 7.3 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Alpha-(1,3)-fucosyltransferase VII
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | KEGG
UniProtKB/SwissProt
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.3 | 22 |
Schering Plough Research Institute
| Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m... |
Arch Biochem Biophys 425: 51-7 (2004)
Article DOI: 10.1016/j.abb.2004.02.039 BindingDB Entry DOI: 10.7270/Q20C4TCS |
More data for this Ligand-Target Pair | |
Alpha-synuclein
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
KEGG
UniProtKB/SwissProt
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Patents
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| PubMed
| n/a | n/a | 4.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assay |
Bioorg Med Chem 28: (2020)
|
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 7.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of ACE by fluorometric assay |
J Nat Prod 51: 357-359 (1988)
Article DOI: 10.1021/np50056a033 BindingDB Entry DOI: 10.7270/Q2XW4M1C |
More data for this Ligand-Target Pair | |
Pancreatic lipase
(Sus scrofa (Pig)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University
Curated by ChEMBL
| Assay Description Inhibition of porcine pancreatic lipase using micellar solution of triolein as substrate preincubated for 5 mins before substrate addition measured a... |
Bioorg Med Chem Lett 22: 6410-2 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.055 BindingDB Entry DOI: 10.7270/Q2668F90 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of DPP4 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 4 secs followed by substrate addition and measured after 30 mins ... |
Eur J Med Chem 151: 145-157 (2018)
Article DOI: 10.1016/j.ejmech.2018.03.041 BindingDB Entry DOI: 10.7270/Q2CZ39SV |
More data for this Ligand-Target Pair | |
Alpha-glucosidase MAL62
(Saccharomyces cerevisiae) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | Reactome pathway
UniProtKB/SwissProt
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Patents
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| Article
| n/a | n/a | 5.20E+9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometry |
Citation and Details
Article DOI: 10.1007/s00044-011-9938-0 BindingDB Entry DOI: 10.7270/Q29W0JBG |
More data for this Ligand-Target Pair | |
Anthrax toxin receptor 2
(Homo sapiens) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School
Curated by ChEMBL
| Assay Description Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli... |
J Med Chem 56: 1940-5 (2013)
Article DOI: 10.1021/jm301558t BindingDB Entry DOI: 10.7270/Q2BP05Q3 |
More data for this Ligand-Target Pair | |
Polypeptide N-acetylgalactosaminyltransferase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
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| Article PubMed
| n/a | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a |
Shanghai Jiao Tong University
Curated by ChEMBL
| Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation constant by SPR analysis |
Bioorg Med Chem 27: 3372-3382 (2019)
Article DOI: 10.1016/j.bmc.2019.06.020 |
More data for this Ligand-Target Pair | |
Polypeptide N-acetylgalactosaminyltransferase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a |
Shanghai Jiao Tong University
Curated by ChEMBL
| Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as association rate by SPR analysis |
Bioorg Med Chem 27: 3372-3382 (2019)
Article DOI: 10.1016/j.bmc.2019.06.020 |
More data for this Ligand-Target Pair | |
Polypeptide N-acetylgalactosaminyltransferase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
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| Article PubMed
| n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
Shanghai Jiao Tong University
Curated by ChEMBL
| Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation rate by SPR analysis |
Bioorg Med Chem 27: 3372-3382 (2019)
Article DOI: 10.1016/j.bmc.2019.06.020 |
More data for this Ligand-Target Pair | |
Polypeptide N-acetylgalactosaminyltransferase 2
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
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| Article PubMed
| n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Jiao Tong University
Curated by ChEMBL
| Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293T cells and using 5-FAM labelled-EA2 peptide as subst... |
Bioorg Med Chem 27: 3372-3382 (2019)
Article DOI: 10.1016/j.bmc.2019.06.020 |
More data for this Ligand-Target Pair | |
Proteasome subunit beta type-1/beta type-5
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 7.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Agricultural and Food Biotechnology
Curated by ChEMBL
| Assay Description Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub... |
Eur J Med Chem 167: 291-311 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.044 |
More data for this Ligand-Target Pair | |
Toll-like receptor 2
(Mus musculus) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 6.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Medical University
Curated by ChEMBL
| Assay Description Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assay |
Eur J Med Chem 179: 233-245 (2019)
Article DOI: 10.1016/j.ejmech.2019.06.059 |
More data for this Ligand-Target Pair | |
Leukocyte adhesion molecule-1
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
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| Article PubMed
| n/a | n/a | 2.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Revotar Biopharmaceuticals AG
Curated by ChEMBL
| Assay Description Inhibition of human L-selectin after 2 hrs |
J Med Chem 50: 1101-15 (2007)
Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6 |
More data for this Ligand-Target Pair | |
P-selectin/P-selectin glycoprotein ligand 1
(Homo sapiens (Human)) | BDBM50085536
(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)Show InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Revotar Biopharmaceuticals AG
Curated by ChEMBL
| Assay Description Inhibition of human P-selectin after 2 hrs |
J Med Chem 50: 1101-15 (2007)
Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6 |
More data for this Ligand-Target Pair | |