BDBM50088631 2-Chloro-3-(3-chloro-phenyl)-5-((R)-pyrrolidin-3-yloxy)-pyridine::CHEMBL10171

SMILES: Clc1cccc(c1)-c1cc(O[C@@H]2CCNC2)cnc1Cl

InChI Key: InChIKey=LJLVBFALIQBYLL-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50088631 (2-Chloro-3-(3-chloro-phenyl)-5-((R)-pyrrolidin-3-y...) Show SMILES Clc1cccc(c1)-c1cc(O[C@@H]2CCNC2)cnc1Cl Show InChI InChI=1S/C15H14Cl2N2O/c16-11-3-1-2-10(6-11)14-7-13(9-19-15(14)17)20-12-4-5-18-8-12/h1-3,6-7,9,12,18H,4-5,8H2/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 10: 1063-6 (2000) BindingDB Entry DOI: 10.7270/Q2PK0HBC
					More data for this Ligand-Target Pair