BDBM50088987 CHEMBL174813::{1-[1-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-ethylcarbamoyl]-2-hydroxy-ethyl}-carbamic acid isobutyl ester; TFA

SMILES: CC(C)COC(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key: InChIKey=USKOLTMETOXNII-NUKBIBLZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50088987 (CHEMBL174813 | {1-[1-(1-Carbamimidoyl-2-hydroxy-pi...) Show SMILES CC(C)COC(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H]1CCCN(C1O)C(N)=N Show InChI InChI=1S/C17H32N6O6/c1-9(2)8-29-17(28)22-12(7-24)14(26)20-10(3)13(25)21-11-5-4-6-23(15(11)27)16(18)19/h9-12,15,24,27H,4-8H2,1-3H3,(H3,18,19)(H,20,26)(H,21,25)(H,22,28)/t10-,11-,12+,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50				Bioorg Med Chem Lett 10: 983-7 (2000) BindingDB Entry DOI: 10.7270/Q2765DKB
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50088987 (CHEMBL174813 | {1-[1-(1-Carbamimidoyl-2-hydroxy-pi...) Show SMILES CC(C)COC(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H]1CCCN(C1O)C(N)=N Show InChI InChI=1S/C17H32N6O6/c1-9(2)8-29-17(28)22-12(7-24)14(26)20-10(3)13(25)21-11-5-4-6-23(15(11)27)16(18)19/h9-12,15,24,27H,4-8H2,1-3H3,(H3,18,19)(H,20,26)(H,21,25)(H,22,28)/t10-,11-,12+,15?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description The compound was tested in vitro for its inhibitory activity against human t-PA enzyme, activity expressed as IC50				Bioorg Med Chem Lett 10: 983-7 (2000) BindingDB Entry DOI: 10.7270/Q2765DKB
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50088987 (CHEMBL174813 | {1-[1-(1-Carbamimidoyl-2-hydroxy-pi...) Show SMILES CC(C)COC(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H]1CCCN(C1O)C(N)=N Show InChI InChI=1S/C17H32N6O6/c1-9(2)8-29-17(28)22-12(7-24)14(26)20-10(3)13(25)21-11-5-4-6-23(15(11)27)16(18)19/h9-12,15,24,27H,4-8H2,1-3H3,(H3,18,19)(H,20,26)(H,21,25)(H,22,28)/t10-,11-,12+,15?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Corvas International, Inc. Curated by ChEMBL					Assay Description The compound was tested in vitro for its inhibitory activity against human Plasmin enzyme, activity expressed as IC50				Bioorg Med Chem Lett 10: 983-7 (2000) BindingDB Entry DOI: 10.7270/Q2765DKB
					More data for this Ligand-Target Pair