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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tissue-type plasminogen activator' and Ligand = 'BDBM50088987'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tissue-type plasminogen activator


(Homo sapiens (Human))		BDBM50088987
PNG
(CHEMBL174813 | {1-[1-(1-Carbamimidoyl-2-hydroxy-pi...)
Show SMILES CC(C)COC(=O)N[C@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H]1CCCN(C1O)C(N)=N
Show InChI InChI=1S/C17H32N6O6/c1-9(2)8-29-17(28)22-12(7-24)14(26)20-10(3)13(25)21-11-5-4-6-23(15(11)27)16(18)19/h9-12,15,24,27H,4-8H2,1-3H3,(H3,18,19)(H,20,26)(H,21,25)(H,22,28)/t10-,11-,12+,15?/m0/s1
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PC sid
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n/an/a>2.50E+3n/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
The compound was tested in vitro for its inhibitory activity against human t-PA enzyme, activity expressed as IC50

Bioorg Med Chem Lett 10: 983-7 (2000)


BindingDB Entry DOI: 10.7270/Q2765DKB
More data for this
Ligand-Target Pair