BDBM50089443 CHEMBL3578109

SMILES: OP(O)(=O)CCOCC(Cn1cnc2c1nc[nH]c2=O)OCCP(O)(O)=O

InChI Key:

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50089443 (CHEMBL3578109) Show SMILES OP(O)(=O)CCOCC(Cn1cnc2c1nc[nH]c2=O)OCCP(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human HGPRT using PRib-PP as the substrate by spectrophotometric method				J Med Chem 60: 7539-7554 (2017) Article DOI: 10.1021/acs.jmedchem.7b00926 BindingDB Entry DOI: 10.7270/Q2J968T1
					More data for this Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50089443 (CHEMBL3578109) Show SMILES OP(O)(=O)CCOCC(Cn1cnc2c1nc[nH]c2=O)OCCP(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human HGPRT				J Med Chem 58: 4822-38 (2015) Article DOI: 10.1021/acs.jmedchem.5b00611 BindingDB Entry DOI: 10.7270/Q2JH3NXV
					More data for this Ligand-Target Pair