BDBM50089534 CHEMBL3578222

SMILES: CNc1nc(SC)nc2n(CCc3ccccc3)nc(-c3ccccc3)c12

InChI Key: InChIKey=OUAIXZWBVHRUSU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50089534 (CHEMBL3578222) Show SMILES CNc1nc(SC)nc2n(CCc3ccccc3)nc(-c3ccccc3)c12 Show InChI InChI=1S/C21H21N5S/c1-22-19-17-18(16-11-7-4-8-12-16)25-26(20(17)24-21(23-19)27-2)14-13-15-9-5-3-6-10-15/h3-12H,13-14H2,1-2H3,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...				J Med Chem 58: 4590-609 (2015) Article DOI: 10.1021/acs.jmedchem.5b00140 BindingDB Entry DOI: 10.7270/Q29025HZ
					More data for this Ligand-Target Pair