BDBM50096459 1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-carboxylic acid 3,5-dichloro-benzylamide::CHEMBL75544
SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(Cl)cc(Cl)c2)c1
InChI Key: InChIKey=FCFGTZIDSYBJHD-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50096459 (1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Curated by ChEMBL | Assay Description Inhibitory activity against serine protease factor Xa (fXa) was determined | Bioorg Med Chem Lett 11: 227-30 (2001) BindingDB Entry DOI: 10.7270/Q2KD1X68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50096459 (1-(3-Carbamimidoyl-benzyl)-4-hydroxy-1H-indole-2-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 771 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma Curated by ChEMBL | Assay Description Inhibitory activity against thrombin was determined | Bioorg Med Chem Lett 11: 227-30 (2001) BindingDB Entry DOI: 10.7270/Q2KD1X68 | |||||||||||
More data for this Ligand-Target Pair |