null
SMILES: CCc1ccc(cc1)C1=C(\C=C\C#Cc2ccc(cc2)C(O)=O)C(C)(C)CCC1
InChI Key: InChIKey=BIPSRDWDLVRJIU-UXBLZVDNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor gamma (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligand | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor alpha | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor gamma (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor beta | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor beta | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor beta (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Ability to inhibit TTNPB-induced transactivation at retinoic acid receptor gamma | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor beta (Homo sapiens (Human)) | BDBM50097821 (4-{(E)-4-[2-(4-Ethyl-phenyl)-6,6-dimethyl-cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Inc Curated by ChEMBL | Assay Description Antagonist activity of TTNPB (10 nM) function at retinoic acid receptor beta | Bioorg Med Chem Lett 11: 765-8 (2001) BindingDB Entry DOI: 10.7270/Q2348JN3 | |||||||||||
More data for this Ligand-Target Pair |