BDBM50102822 CHEMBL3339360

SMILES: COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=DQVUCDBOFDTXMU-LALXJTNGSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50102822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate by HTRF assay				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-KIT (unknown origin)				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of RON (unknown origin)				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin)				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126630
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50102822 (CHEMBL3339360) Show SMILES COc1cc2c(Oc3ccc(CC(=O)N\N=C\c4ccc(cc4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H32F4N4O4/c1-43-30-19-25-27(20-31(30)44-16-4-15-41-13-2-3-14-41)38-12-11-28(25)45-29-10-7-23(17-26(29)34)18-32(42)40-39-21-22-5-8-24(9-6-22)33(35,36)37/h5-12,17,19-21H,2-4,13-16,18H2,1H3,(H,40,42)/b39-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin)				Eur J Med Chem 87: 508-18 (2014) Article DOI: 10.1016/j.ejmech.2014.09.095 BindingDB Entry DOI: 10.7270/Q24X59KD
					More data for this Ligand-Target Pair