BindingDB PrimarySearch

BDBM50103601 CEFTRIAXONE::CHEBI:29007::Ceftriaxone

SMILES: [H][C@@]1(NC(=O)C(=N/OC)\c2csc(N)n2)C(=O)N2C(C(O)=O)=C(CSc3nc(=O)c(O)nn3C)CS[C@]12[H]

InChI Key: InChIKey=VAAUVRVFOQPIGI-SPQHTLEESA-N

Data: 38 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 50103601
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of CYP3A4 in human liver microsomes using testosterone substrate by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of CYP2C19 in human liver microsomes using omeprazole substrate by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2J2 (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of CYP2C9 in human liver microsomes using tolbutamide substrate by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of CYP2D6 in human liver microsomes using bufuralol substrate by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Curated by ChEMBL					Assay Description Inhibition of DAAO (unknown origin)				J Med Chem 58: 7258-72 (2015) BindingDB Entry DOI: 10.7270/Q2SF2XZQ
Johns Hopkins University Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
ChanTest Corporation Curated by ChEMBL					Assay Description Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunits				Sci Rep 3: (2013) Article DOI: 10.1038/srep02100 BindingDB Entry DOI: 10.7270/Q2RB77K2
ChanTest Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Bocillin FL binding to PBP2b in Streptococcus pneumoniae isolate 8819 harboring E333G, I361L, E369D, S412P, N422Y, T426K, Q427L, Q438E,...				Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/aac.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Bocillin FL binding to PBP2b in laboratory-derived Streptococcus pneumoniae isolate R6				Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/aac.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae isolate 8882 Bocillin FL binding to PBP2b 443SSNA mutant				Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/aac.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Bocillin FL binding to PBP2b PBP2b 443SSNA mutant in Streptococcus pneumoniae isolate 8009 harboring E333G, N470K, E476G, T489S, E506D,...				Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/aac.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91
					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of Bocillin FL binding to Streptococcus pneumoniae isolate 8865 PBP2b				Antimicrob Agents Chemother 54: 4510-2 (2010) Article DOI: 10.1128/aac.00590-10 BindingDB Entry DOI: 10.7270/Q29W0J91
					More data for this Ligand-Target Pair
Peptidoglycan D,D-transpeptidase MrdA (Escherichia coli)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Cell division protein FtsI (Peptidoglycan synthetase) (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	901	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to methicillin-susceptible Staphylococcus aureus ATCC 29213 penicillin-binding protein 1				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Penicillin-binding protein (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to methicillin-susceptible Staphylococcus aureus ATCC 29213 penicillin-binding protein 2				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>9.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to methicillin-resistant Staphylococcus aureus OC 3726 penicillin-binding protein 2a				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Penicillin-binding protein 3 (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to methicillin-susceptible Staphylococcus aureus ATCC 29213 penicillin-binding protein 3				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Penicillin-binding protein (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of bocillin FL binding to methicillin-susceptible Staphylococcus aureus ATCC 29213 penicillin-binding protein 4				Antimicrob Agents Chemother 51: 2621-4 (2007) Article DOI: 10.1128/aac.00029-07 BindingDB Entry DOI: 10.7270/Q2VH5RN2
					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by compet...				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competit...				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding a...				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by co...				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP1A by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP1A by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2X by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2B by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP1A by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2X by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2X by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2B by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin binding protein 2' (Staphylococcus aureus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 1A (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP1A by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2x (Streptococcus pneumoniae)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2X by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2B by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Penicillin-binding protein 2B (Streptococcus pneumoniae serotype 4 (strain ATCC B...)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hershey Medical Center Curated by ChEMBL					Assay Description Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2B by competitive binding assay				Antimicrob Agents Chemother 54: 1670-7 (2010) Article DOI: 10.1128/aac.00019-10 BindingDB Entry DOI: 10.7270/Q2B56NK6
Hershey Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells				Life Sci 70: 1861-74 (2002) Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Rattus norvegicus)	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells				Life Sci 70: 1861-74 (2002) Article DOI: 10.1016/s0024-3205(02)01500-x BindingDB Entry DOI: 10.7270/Q2SN0CV2
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A (Homo sapiens (Human))	BDBM50103601 (CEFTRIAXONE \| CHEBI:29007 \| Ceftriaxone) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tongji University Curated by ChEMBL					Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin substrate by LC-MS/MS method				Drug Metab Dispos 41: 60-71 (2012) Article DOI: 10.1124/dmd.112.048264 BindingDB Entry DOI: 10.7270/Q2K0761G
Tongji University Curated by ChEMBL					More data for this Ligand-Target Pair