null
SMILES: CCc1nccn1-c1ccccc1C(=O)Nc1ccc(cc1)C(=O)N(C)c1ccc(C)cc1OCc1ccc(cc1)C(=O)N1CCN(C)CC1
InChI Key: InChIKey=BCEZGQLWWKMCIT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1a receptor (RAT) | BDBM50108499 (1N-methyl-1N-{4-methyl-2-[4-(4-methylhexahydro-1-p...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V1A) receptor in rat liver membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Rattus norvegicus (Rat)) | BDBM50108499 (1N-methyl-1N-{4-methyl-2-[4-(4-methylhexahydro-1-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 445 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yamanouchi Pharmaceutical Co. Ltd. Curated by ChEMBL | Assay Description Evaluated for the binding affinity towards vasopressin (V2) receptor in rat kidney membrane using [3H]AVP as radioligand | Bioorg Med Chem Lett 12: 229-32 (2001) BindingDB Entry DOI: 10.7270/Q2R78FQP | |||||||||||
More data for this Ligand-Target Pair |