BDBM50108567 5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-sulfonic acid amide::Benzolamide, BZM::CHEMBL108982

SMILES: NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1

InChI Key: InChIKey=CYPRFFCTABNEJY-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on human Carbonic anhydrase II				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on bovine Carbonic anhydrase IV				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibitory effect on human carbonic anhydrase I				J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50108567 (5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-...) Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C9H10N4O4S3/c10-20(16,17)9-12-11-8(18-9)13-19(14,15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,13)(H2,10,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida					Assay Description Inhibition assay using carbonic anhydrases.				Biochemistry 48: 1322-31 (2009) Article DOI: 10.1021/bi802035f BindingDB Entry DOI: 10.7270/Q2HX1B94
					More data for this Ligand-Target Pair