BDBM50109671 4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL147365

SMILES: COc1cc(OC)nc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key: InChIKey=PBQXMKQAIAUNQN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50109671 (4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfo...) Show SMILES COc1cc(OC)nc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-23(14)27-33(28,29)19-8-6-5-7-18(19)16-9-11-17(12-10-16)22-24-20(30-3)13-21(25-22)31-4/h5-13,27H,1-4H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin A receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50109671 (4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfo...) Show SMILES COc1cc(OC)nc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C Show InChI InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-23(14)27-33(28,29)19-8-6-5-7-18(19)16-9-11-17(12-10-16)22-24-20(30-3)13-21(25-22)31-4/h5-13,27H,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to CHO cells stably expressing human Endothelin B receptor.				Bioorg Med Chem Lett 12: 517-20 (2002) BindingDB Entry DOI: 10.7270/Q2GF0STQ
					More data for this Ligand-Target Pair