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Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50109671'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1 receptor


(Homo sapiens (Human))		BDBM50109671
PNG
(4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfo...)
Show SMILES COc1cc(OC)nc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-23(14)27-33(28,29)19-8-6-5-7-18(19)16-9-11-17(12-10-16)22-24-20(30-3)13-21(25-22)31-4/h5-13,27H,1-4H3
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Similars
PubMed
 220n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to CHO cells stably expressing human Endothelin A receptor.

Bioorg Med Chem Lett 12: 517-20 (2002)


BindingDB Entry DOI: 10.7270/Q2GF0STQ
More data for this
Ligand-Target Pair